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In type 2 or so-called juvenile GM1 gangliosidosis, the onset is between 12 and 24 months, with survival for 3 to 10 years. The rst sign is usually dif culty in walking, with frequent falls, followed by awkwardness of arm movements, loss of speech, severe mental regression, gradual development of spastic quadriparesis and pseudobulbar palsy (dysarthria, dysphagia, drooling), and seizures. Retinal changes are variable usually they are absent, but macular red spots may be seen at the age of 10 to 12 years; vision is usually retained, but squints (comitant) are common. There is a facial dysmorphism resembling that of the Hurler syndrome, and the liver and spleen are enlarged. Important laboratory ndings are hypoplasia of the thoracolumbar vertebral bodies, mild hypoplasia of the acetabula, and the presence in the bone marrow of histiocytes with clear vacuoles or wrinkled cytoplasm. As noted on page 807, leukocytes and cultured skin broblasts show a de ciency or absence of -galactosidase activity. GM1 ganglioside accumulates in the cerebral neurons.

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Kansas Kansas State University (B.Arch.) Department of Architecture College of Architecture, Planning, and Design Manhattan, KS 66506 http://capd.ksu.edu/

Virtual servers can be stopped, started, paused, and resumed like actual servers. For example, to stop and then restart the default IMAP virtual server, right-click on the IMAP4 container under the Protocols container in System Manager and select Stop or click the Stop button on the toolbar. Stopping the default IMAP virtual server has no effect on the state of operation of any other virtual server on the machine, including other IMAP4 virtual servers (if you had created some). To restart, right-click on the virtual server and select Restart.

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Some of the most involved and time-consuming cases are those handled by caseworkers in public welfare agencies, responsible for making allotments of public funds. These social workers have a triple responsibility prudent handling of the taxpayers money, wise counseling, and provision of adequate relief funds to each needy client who applies for help. Other caseworker responsibilities include:

To help new teachers, a number of schools have begun mentor programs, often nanced by the state. Selected experienced teachers, many of them with special training, assist beginners in the rst year or two. Often called mentors, these teachers serve in an advisory rather than a supervisory role. They do not evaluate beginners for job retention. Rather, they help beginners with such problems as preparing lessons, nding materials, organiz-

Recruiting firms. Some job opportunities are listed with recruiting firms. These firms provide needed services to both organizations and applicants.

Divide-and-conquer algorithms often follow a generic pattern: they tackle a problem of size n by recursively solving, say, a subproblems of size n/b and then combining these answers in O(nd ) time, for some a, b, d > 0 (in the multiplication algorithm, a = 3, b = 2, and d = 1). Their running time can therefore be captured by the equation T (n) = aT ( n/b ) + O(n d ). We next derive a closed-form solution to this general recurrence so that we no longer have to solve it explicitly in each new instance. 51

Completing the following sentences about your baby s favorite things is a good way to decide which signs to introduce to your baby as you start expanding his signing vocabulary. For example, if your baby s favorite nursery rhyme is Hickory Dickory Dock, the mouse sign might be a good choice. My baby s favorite drink is ___________________________________ . My baby s favorite snack is ___________________________________ . My baby s favorite fruit is ____________________________________ . My baby s favorite playtime toy is ______________________________ . My baby s favorite bedtime toy is ______________________________ . My baby s favorite bathtime toy is ______________________________ . My baby s favorite pet is _____________________________________ . My baby s favorite farm animal is ______________________________ . My baby s favorite zoo animal is _______________________________ . My baby s favorite book is ___________________________________ . My baby s favorite song is ____________________________________ . My baby s favorite nursery rhyme is ____________________________ .

Number Empl. Homemaker/Home Health Aide Information and Record Clerk Personal Home Care Aide Licensed Practical Nurse (LPN) Mail Clerk 615,000 5.1 million 414,000 700,000 188,000

proposals with rules stored for the sales managers who have the best expertise to respond to the proposal. Expression Filters use an Oracle operator EVALUATE in a SQL WHERE clause and again rely on function-based indexes for performance. Expression rules use a collection of distinct data attributes (called attribute sets) and Oracle object types. The PL/SQL APIs for creating these attribute sets and mapping them to the tables where the rule expressions will be stored requires two steps: First you must disable the Oracle Data Dictionary realm, and then you must disable the application realm (Sample DBV Application):

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