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In the golden rule regime (wo ~ .Do ~ J<i.) considered here, the integrals on last term on the right-hand side of (7.104) can be done (Problem 7.1) and we find 9 that

The promises of biotechnology in the Pharmaceutical industry have yet to materialize in a meaningful way. Although most traditional pharma ceutical companies are developing drugs created through recombinant DNA and other biotech methods, biotech products represent less than 10 percent of the pharmaceutical market. Speculative investment in biotech, like that in the dot-coms, has dried up. Despite a drug develop ment pipeline lled with numerous biotech drugs, many have failed to survive the gauntlet of clinical trials imposed by regulatory agencies. Moreover, the drugs that manage to reach the marketplace tend to be signi cantly more expensive than traditional pharmaceuticals. Despite all of the hype, biopharmaceuticals (pharmaceuticals created using biotechnology) represent only about $35 billion of the quarter-trilliondollar pharmaceutical market. Furthermore, most of these products are from a handful of companies, notably Amgen, Boehringer Ingelheim, Biogen, Genetech, and Idec Pharmaceuticals. The greatest challenge and potential of biopharmaceuticals are rooted in the drug development process, which is illustrated in Figure 1.3. The rst step in the process practiced in the United States, drug discovery, can take anywhere from 2 to 20 years or more to complete. For example, a representative of a pharmaceutical company working with a shaman in the Amazon basin to identify plants of medicinal value might uncover a plant used by natives to treat a particular disease for generations. How ever, the researcher can t simply bring the plant to his laboratory in the United States, identify and then synthesize the active ingredients, and be gin marketing the drug for particular uses. A claim of ef cacy, even if backed by records of centuries of use in folk medicine, isn t suf cient for a

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You may want to create a new account for the following reasons: You require an additional account to track another income or expense item. You must divide an account into subaccounts to track income and expenses more ef ciently. You open a new bank account or acquire a new credit source and must create a corresponding Balance Sheet account. You are setting up accounts for online banking and online payment. To add a new income or expense account, follow these steps: 1. Go to the Company Navigator screen and click the Chart of Accounts icon, as shown in Figure 6-2. Your Chart of Accounts appears.

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(7.105)

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Record-Keeping Goals . . . . . . . . . . . . . . . . . . . . The Essential Order for Entering Data . . . . . . . . . . . A Checklist for Establishing Your Opening Balances . . . Entering Opening Balances with the EasyStep Interview Entering Past Customer Sales and Accounts Receivable Entering Past Accounts Payable (Vendor) Information . Entering Balance Sheet Account Opening Balances . . . Liabilities . . . . . . . . . . . . . . . . . . . . . . . . Assets . . . . . . . . . . . . . . . . . . . . . . . . . Equity Accounts . . . . . . . . . . . . . . . . . . . . Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107 108 109 109 110 113 115 115 116 117 118

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(7.106) (7.107) (7.108)

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